DigiSKIN atlas

Single-cell RNA sequencing (scRNA-seq) has transformed the study of skin biology by enabling high-resolution analysis of gene expression at the level of individual cells. This approach allows researchers to uncover cellular diversity, detect rare or previously unrecognized cell populations, and refine diagnostic strategies in dermatology.

We developed the DigiSkin Atlas, a comprehensive and openly accessible scRNA-seq resource of mouse skin. This atlas integrates 20 independent datasets, encompassing 406,563 cells collected across diverse developmental stages and physiological conditions. Through an interactive framework, DigiSkin supports detailed exploration of gene expression profiles, facilitates validation of established cellular markers, and enables investigation of transcriptional dynamics linked to development, tissue injury, and aging.

The Atlas is available under the interface below and its detailed description and how-to-use instruction will be available as a publication (submitted), currently available per email request.

The DigiSKIN atlas is also available at the following link.